"It is revealed in the 12th episode, that a “senior agent” was holding onto Skye as a baby whilst he was mortally wounded with a gunshot wound to the neck with which he later bled out. In a much later episode, it is revealed that Agent Garrett - also a senior agent - received a third degree burn to the neck which he presented to Skye in the interrogation room. It is not yet known if there is any connection to Garrett and Skye.” [x]
Oh my. Did you catch this?
Coulson: “Skye, please tell me something good.”
Skye: “We have Internet.”
Coulson: “Yay. And boy, have I lowered my expectations.”